It may sound very tempting to use CBD and alcohol together, but they both may affect how your body works.

There are many ways to combine CBD and alcohol, and their effects vary depending on the way you consumed it. While mixing CBD and alcohol is not recommended, CBD has several potential therapeutic effects on the side effects of alcohol when taken separately.

You may experience drowsiness, dehydration, and confusion as side effects. 

Keep reading if you want to understand what happens when using CBD and alcohol simultaneously.

Can You Mix Cannabis And Alcohol?

No, you should not mix CBD and alcohol because they may amplify each other’s effects.

The joint effects of alcohol are known to promote relaxation and decrease inhibitions.

CBD shares similar effects with alcohol by stimulating calmed and relaxed behaviors.

According to a study from the Neuropsychology Journal, CBD helps people feel comfortable with public speaking. 

Additionally, CBD has shown sleep-improving properties among users. 

Research from The Permanente Journal in 2019 found that taking a daily dose of 25-75 mg of CBD daily can improve your mood and the quality of your sleep.  

Since both alcohol and CBD share similar properties, the combination may amplify the effects, causing increasing sleepiness among users.

A small clinical trial from the Psychopharmacology Journal analyzed the effects of CBD and alcohol among 10 participants. 

The participants were administered 1 g of alcohol and 200 mg of CBD per 2.2 pounds or 1 Kg of body weight.

The findings showed that both CBD and alcohol caused significant impairments in motor performances, such as walking, jumping, and running.

However, you should note that CBD concentrations in the study are higher than regular CBD doses. 

Another limitation is the small sample size of the research.

Unfortunately, there is not much research on the effects of CBD and alcohol on the body.

What Are The Effects Of CBD On Alcohol Users?

While mixing CBD and alcohol may not be a good idea, recent research has shown that CBD may help in reducing alcohol side effects when not taken together. 

Taking too much alcohol may lead to severe consequences such as damage to your body cells and increased risk of long-term problems.

However, animal studies have shown that CBD can protect cells from alcohol consumption. 

A research paper from the Pharmacology, Biochemistry, and Behavior Journal showed that CBD could help with reducing the damage to brain cells caused by alcohol in rats. 

According to the paper, a CBD gel of 5% helped decrease the degeneration of neurons in rats by approximately 49%.

Another study from the Free Radical Biology Medicine Journal observed the effects of CBD on the liver of mice. 

The findings stated that CBD protected the liver by reducing autophagy (your body’s way of removing damaged cells) caused by alcohol. 

However, all studies regarding CBD and alcohol-induced damaged cells have been made on animals so far. 

Further studies are needed to understand the actual effect of CBD on cell damage caused by alcohol in humans.

Additionally, CBD can potentially help in reducing drug addiction. 

A review from the Neuropsychopharmacology Journal stated that CBD could prevent relapse among drug addicts. 

The review stated that CBD could decrease alcohol intake and desire to consume alcohol.

Are There Any Risks Of Mixing CBD And Alcohol?

There is a potential risk that CBD can intensify the effects of alcohol when combined. 

Since both CBD and alcohol provide relaxing effects and inhibit stimulations, they can increase drowsiness leading to behavioral changes among users.

A study from the Psychopharmacology Journal found that CBD and alcohol can lead to impaired motor functions meaning that you may have difficulty walking, dancing, or jumping.

However, it is difficult to understand the extent of the risks associated with mixing CBD and alcohol with little research. 

Besides, recent research analyzed the effects of large concentrations of CBD and alcohol rather than occasional use of the combination.

Thus, scientists do not know the risks associated with CBD and alcohol for moderate or occasional consumption.

Therefore, it is wiser to be cautious when taking a mixture of CBD and alcohol due to their potent effects.

While the effects of CBD and alcohol will also differ across users, you should start with small amounts and gradually build up to get your desired outcome. 

Can CBD Help With Hangovers?

CBD is not an effective method to help with hangovers, but it can relieve some of the hangover symptoms, namely headaches and motion sickness. 

Headaches are caused by dehydration and a potential imbalance in your endocannabinoid system (ECS).

According to a Cannabis and Cannabinoid Research report, a significant difference in anandamide levels was seen in people with migraines.

Anandamide is an essential hormone in the ECS that helps to regulate the endocrine system.

However, it should be noted that the study did not observe the effect of CBD and anandamide on migraines. 

A paper from the Translational Psychiatry Journal showed that CBD increased anandamide levels by inhibiting an enzyme that breaks down the hormone.

Therefore, CBD can help to alleviate your terrible migraines from the hangover by increasing the concentration of anandamide in your body.

CBD Oil And Alcohol Withdrawal

According to The Journal of Neurotoxicity Research, there is no data to justify CBD usage to manage alcoholism or withdrawal. 

Furthermore, some findings suggest that cannabinoid receptor antagonists could be effective in the treatment of alcoholism.

As alcohol and cannabinoid agonists (in different forms) are ingested together, adverse side effects result; however, when CB1 antagonists are administered, alcohol intake is significantly reduced.

Yet, it is not uncommon for a raw natural product to have both potentially beneficial and detrimental effects. 

It seems to be the case of CBD since an experiment (in mice) by The Journal Free Radical Biology and Medicine suggests that CBD could help protect the liver from alcohol-induced steatosis. 

Alcohol-induced steatosis is the progressive damage of alcohol on the liver. 

The findings of this experiment show that cannabidiol protects the mouse liver from acute alcohol-induced steatosis through a variety of mechanisms.

The mechanisms include reduced oxidative stress, decreased JNK MAPK activation, and increased autophagy.

Autophagy is increased by cannabidiol in CYP2E1-expressing HepG2 cells and mouse liver. 

Significantly, cannabidiol can counteract the effects of alcohol on autophagy. 

However, we are yet to prove that those benefits are also applicable to humans.